Not all interesting network activity occurs in cortex. Networks in the spinal cord, the long thin tubular structure extending downwards from the neck, is responsible for setting up rhythmic motor activity needed for moving around.
How do these so-called central pattern generators work?
Today’s guest has, together with colleagues in Copenhagen, developed a neuron-based network theory for how these rhythmic oscillations may arise even without pace-maker neurons driving the collective.
Links to papers/books mentioned in the podcast:
- Lindén et al: “Movement is governed by rotational neural dynamics in spinal motor networks”, Nature, 2022
- Hennequin et al: “Optimal Control of Transient Dynamics in Balanced Networks Supports Generation of Complex Movements”, Neuron, 2014
- Stroud et al: “Motor primitives in space and time via targeted gain modulation in cortical networks”, Nature Neuroscience, 2018
- Rajan and Abbott: “Eigenvalue Spectra of Random Matrices for Neural Networks”, Physical Review Letters, 2006
- Izhikevich: “Dynamical Systems in Neuroscience”, MIT Press, 2006
- Dayan and Abbott: “Theoretical Neuroscience”, MIT Press, 2001
Link to home page of lab of Rune Berg (where Henrik’s work was done):
The podcast was recorded on November 22, 2023 and lasts 1 hour and 26 minutes.
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2 replies on “#6: On central pattern generators in the spinal cord – with Henrik Lindén”
Dynamical Systems in Neuroscience: The geometry of excitability and bursting – Eugene Izhikevich
was also mentioned
Thanks. A link to this book is now added. 🙂