A holy grail of the multiscale approach for physical brain modelling is to link the different scales from molecules, via cells and local neural networks, up to whole-brain models.
The goal of the Virtual Brain Twin project, lead by today’s guest, is to use personalized human whole-brain models to aid clinicians in treating brain ailments.
The podcast discusses how such models are presently made using neural field models, starting with neuron population dynamics rather than molecular dynamics.
Links:
- Homepage of The Virtual Brain (TVB)
- Wang et al.: “Virtual brain twins: from basic neuroscience to clinical use”, National Science Review (2024)
- Sanz-Leon et al.: et al.: “Mathematical framework for large-scale brain network modeling in The Virtual Brain”, NeuroImage (2015)
- Einevoll et al.: “The scientific case for brain simulations”, Neuron (2019)
- Wikipedia page of Viktor Jirsa
The podcast was recorded on November 22nd, 2024 and lasts 1 hour and 55 minutes.
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